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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Abstract:

Background: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease; treatment strategies have historically been determined by this binary categorisation. Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disease and ulcerative colitis. We undertook the largest genotype association study, to date, in widely used clinical subphenotypes of inflammatory...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Name:
Medical Research Foundation
Grant:
C0482
More from this funder
Name:
NIAID NIH HHS
Grant:
AI067068
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Name:
Medical Research Council
Grant:
1202121
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Name:
Wellcome Trust
Grant:
083948/Z/07/Z
Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
387
Issue:
10014
Pages:
156-167
Publication date:
2015-10-18
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pmid:
26490195
Language:
English
Keywords:
Pubs id:
pubs:586935
UUID:
uuid:90339b42-3f44-477c-9f23-25f9f98db271
Local pid:
pubs:586935
Source identifiers:
586935
Deposit date:
2018-08-10

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