- Abstract:
-
Tissue microstructure, in particular the alignment of myocytes (fibre direction) and their lateral organisation into sheets, is fundamental to cardiac function. We studied the effect of microstructure on contraction in a computational model of rat left ventricular electromechanics. Different fibre models, globally rule-based or locally optimised to DT-MRI data, were compared, in order to understand whether a subject-specific fibre model would enhance the predi...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.1MB)
-
- Publisher copy:
- 10.1371/journal.pone.0092792
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 9
- Issue:
- 4
- Pages:
- e92792
- Publication date:
- 2014-04-02
- Acceptance date:
- 2014-02-26
- DOI:
- EISSN:
-
1932-6203
- Pubs id:
-
pubs:458678
- URN:
-
uri:90311d6b-88ce-4bd8-b562-c1f2536847e0
- UUID:
-
uuid:90311d6b-88ce-4bd8-b562-c1f2536847e0
- Local pid:
- pubs:458678
- Paper number:
- ARTN e92792
- Language:
- English
- Keywords:
- Copyright holder:
- Carapella et al.
- Copyright date:
- 2014
- Notes:
- © 2014 Carapella et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Quantitative study of the effect of tissue microstructure on contraction in a computational model of rat left ventricle
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