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Journal article

Inhibition of nitric oxide synthase does not impair spatial learning.

Abstract:

Nitric oxide (NO), a putative intercellular messenger in the CNS, may be involved in certain forms of synaptic plasticity and learning. This article reports a series of experiments investigating the effects of N omega-nitro-L-arginine methyl ester (L-NAME) upon various forms of learning and memory in the watermaze. L-NAME (75 mg/kg, i.p., sufficient to bring about > 90% inhibition of NO synthesis in brain) produced an apparent impairment in spatial learning when given to naive rats during ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Journal of neuroscience : the official journal of the Society for Neuroscience More from this journal
Volume:
14
Issue:
12
Pages:
7404-7414
Publication date:
1994-12-01
EISSN:
1529-2401
ISSN:
0270-6474
Language:
English
Keywords:
Pubs id:
pubs:4466
UUID:
uuid:901e7359-72e4-47e8-bd18-fe44a1972657
Local pid:
pubs:4466
Source identifiers:
4466
Deposit date:
2012-12-19

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