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Microvessel networks in pre-formed in artificial clinical grade dermal substitutes in vitro using cells from haematopoietic tissues

Abstract:

Forming a microcirculation is critical for vascularisation of artificial skin substitutes. One strategy to improve speed of grafting is to pre-form microvascular networks in the substitute before applying to a wound. For clinical application, this requires sufficient functional endothelial cell numbers. In vitro endothelial colony forming cells (ECFCs) derived cells were expanded from cord and adult blood donations and co-cultured with human dermal fibroblasts or bone marrow mesenchymal stem/...

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Publisher copy:
10.1016/j.burns.2011.12.019

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Burns More from this journal
Volume:
38
Issue:
5
Pages:
691-701
Publication date:
2012-08-01
DOI:
EISSN:
1879-1409
ISSN:
0305-4179
Language:
English
Keywords:
Pubs id:
pubs:335192
UUID:
uuid:90197558-f97a-4f02-b89c-8a8b5e2d9df5
Local pid:
pubs:335192
Source identifiers:
335192
Deposit date:
2013-11-16

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