- Abstract:
-
Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine that plays an important role in the immune system and local inflammatory response. LTA is expressed in atherosclerotic plaques and has been implicated in the pathogenesis of atherosclerosis and coronary heart disease (CHD). Polymorphisms in the gene encoding lymphotoxin-alpha (LTA) on Chromosome 6p21 have been associated with susceptibility to CHD, but results in different studies appear to be conflicting. We examined the association of s...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 317.4kb)
-
- Publisher copy:
- 10.1371/journal.pgen.0020107
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 2
- Issue:
- 7
- Pages:
- Article: e107
- Publication date:
- 2006-07-05
- DOI:
- EISSN:
-
1553-7404
- ISSN:
-
1553-7390
- URN:
-
uuid:9004398c-e259-4746-9f30-f55da1156893
- Source identifiers:
-
33544
- Local pid:
- pubs:33544
- Language:
- English
- Keywords:
- Copyright holder:
- Clarke et al.
- Copyright date:
- 2006
- Notes:
- Copyright 2006 Clarke et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study
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British Heart Foundation
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Medical Research Council
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Cancer Research UK
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Tobacco Products Research Trust of the UK Department of Health Independent Scientific Committee on Smoking and Health
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Oxford National Health Service Genetic Knowledge Park
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