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A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioning.

Abstract:

The AMPA receptor subunit glutamate receptor 1 (GluR1 or GluR-A) contributes to amygdala-dependent emotional learning. It remains unclear, however, to what extent different amygdala pathways depend on GluR1, or other AMPA receptor subunits, for proper synaptic transmission and plasticity, and whether GluR1-dependent long-term potentiation (LTP) is necessary for auditory and contextual fear conditioning. Here, we dissected the role of GluR1 and GluR3 (GluR-C) subunits in AMPA receptor-dependen...

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Publication status:
Published

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Journal:
Journal of neuroscience : the official journal of the Society for Neuroscience More from this journal
Volume:
27
Issue:
41
Pages:
10947-10956
Publication date:
2007-10-01
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Language:
English
Keywords:
Pubs id:
pubs:21905
UUID:
uuid:8ffc1dec-2c6e-48ea-847e-9d3497466f80
Local pid:
pubs:21905
Source identifiers:
21905
Deposit date:
2012-12-19

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