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P-selectin expression tracks cerebral atrophy in Mexican-Americans

Abstract:
Background and Purpose: We hypothesized that the P-selectin (SELP) gene, localized to a region on chromosome 1q24, pleiotropically contributes to increased blood pressure and cerebral atrophy. We tested this hypothesis by performing genetic correlation analyses for 13 mRNA gene expression measures from P-selectin and 11 other genes located in 1q24 region and three magnetic resonance imaging derived indices of cerebral integrity. Methods: The... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3389/fgene.2012.00065

Authors


Kochunov, P More by this author
Lancaster, J More by this author
Curran, JE More by this author
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Publisher:
Frontiers Media S.A. Publisher's website
Journal:
Frontiers in genetics Journal website
Volume:
3
Pages:
Article: 65
Publication date:
2012-05-01
DOI:
EISSN:
1664-8021
URN:
uuid:8fc183b9-cfe5-480d-9720-74c8a82b9c05
Source identifiers:
445999
Local pid:
pubs:445999

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