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Microvascular dilation in response to occlusion: a coordinating role for conducted vasomotor responses.

Abstract:

In rat cremasteric microcirculation, mechanical occlusion of one branch of an arteriolar bifurcation causes an increase in flow and vasodilation of the unoccluded daughter branch. This dilation has been attributed to the operation of a shear stress-dependent mechanism in the microcirculation. Instead of or in addition to this, we hypothesized that the dilation observed during occlusion is the result of a conducted signal originating distal to the occlusion. To test this hypothesis, we blocked...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology, BHF Centre of Research Excellence
Role:
Author
Journal:
American journal of physiology. Heart and circulatory physiology
Volume:
279
Issue:
1
Pages:
H279-H284
Publication date:
2000-07-05
EISSN:
1522-1539
ISSN:
0363-6135
URN:
uuid:8fa9ee25-0e80-436e-87a3-c57076e4a8e2
Source identifiers:
106372
Local pid:
pubs:106372

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