- Abstract:
-
A provisional matrix consisting of fibrin and fibronectin (FN) is deposited at sites of tissue damage and repair. This matrix serves as a scaffold for fibroblast migration into the wound where these cells deposit new matrix to replace lost or damaged tissue and eventually contract the matrix to bring the margins of the wound together. Tenascin-C is expressed transiently during wound repair in tissue adjacent to areas of injury and contacts the provisional matrix in vivo. Using a synthetic mod...
Expand abstract - Publisher copy:
- 10.1091/mbc.e02-05-0292
-
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- Journal:
- Molecular biology of the cell
- Volume:
- 13
- Issue:
- 10
- Pages:
- 3601-3613
- Publication date:
- 2002-10-05
- DOI:
- EISSN:
-
1939-4586
- ISSN:
-
1059-1524
- URN:
-
uuid:8f8a6bd7-f81f-4a6a-b6ff-d8f7f50d99a6
- Source identifiers:
-
225493
- Local pid:
- pubs:225493
- Language:
- English
- Keywords:
- Copyright date:
- 2002
Journal article
Tenascin-C modulates matrix contraction via focal adhesion kinase- and Rho-mediated signaling pathways.
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