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Pairwise comparisons of mitochondrial DNA sequences in subdivided populations and implications for early human evolution.

Abstract:

We consider the effect on the distribution of pairwise differences between mitochondrial DNA sequences of the incorporation into the underlying population genetics model of two particular effects that seem realistic for human populations. The first is that the population size was roughly constant before growing to its current level. The second is that the population is geographically subdivided rather than panmictic. In each case these features tend to encourage multimodal distributions of pa...

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Publication status:
Published

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Authors


Marjoram, P More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics, BHF Centre of Research Excellence, Biomedical Research Centre, MPLS, Statistics
Journal:
Genetics
Volume:
136
Issue:
2
Pages:
673-683
Publication date:
1994-02-05
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:8f70e82a-a1d0-4954-9dee-e7fe0ea6fe19
Source identifiers:
69417
Local pid:
pubs:69417

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