The ratio between class II and class I collagenase determines the amount of neutral protease activity required for efficient islet release from the rat pancreas.

Brandhorst, H; Alt, A; Huettler, S; Raemsch-Guenther, N; Kurfuerst, M; Bretzel, R; Brandhorst, D

Journal article

The ratio between class II and class I collagenase determines the amount of neutral protease activity required for efficient islet release from the rat pancreas.

Abstract:: Previous investigations clearly showed that the successful release of islets from the pancreas is mediated by both neutral protease (NP) and collagenase, consisting of subclasses I and II showing different capacities to cleave islets from the pancreas. Since no informations about the optimal ratio between class II and class I collagenase (II/I-ratio) are available yet, the present study sought to evaluate the efficient range for the II/I-ratio. METHODS: Following intraductal pancreas collagen...
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APA Style

Brandhorst, H., Alt, A., Huettler, S., Raemsch-Guenther, N., Kurfuerst, M., Bretzel, R., & Brandhorst, D. (2005). The ratio between class II and class I collagenase determines the amount of neutral protease activity required for efficient islet release from the rat pancreas. Transplantation Proceedings, 37(1), 215–216.

MLA Style

Brandhorst, H., et al. “The Ratio between Class II and Class I Collagenase Determines the Amount of Neutral Protease Activity Required for Efficient Islet Release from the Rat Pancreas.” Transplantation Proceedings, vol. 37, no. 1, 2005, pp. 215–16.

Chicago Style

Brandhorst, H, A Alt, S Huettler, N Raemsch-Guenther, M Kurfuerst, R Bretzel, and D Brandhorst. 2005. “The Ratio between Class II and Class I Collagenase Determines the Amount of Neutral Protease Activity Required for Efficient Islet Release from the Rat Pancreas.” Transplantation Proceedings 37 (1): 215–16.
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Publisher copy:: 10.1016/j.transproceed.2004.12.256

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+ Brandhorst, H More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Surgical Sciences

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Author

+ Alt, A More by this author

Role:

Author

+ Huettler, S More by this author

Role:

Author

+ Raemsch-Guenther, N More by this author

Role:

Author

+ Kurfuerst, M More by this author

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Bibliographic Details

Journal:: Transplantation proceedings More from this journal
Volume:: 37
Issue:: 1
Pages:: 215-216
Publication date:: 2005-01-01
DOI:: 10.1016/j.transproceed.2004.12.256
EISSN:: 1873-2623
ISSN:: 0041-1345

Item Description

Language:: English
Keywords:: Cell Survival

Collagenases

Peptide Hydrolases

Cell Separation

Animals

Rats

Pancreas

Islets of Langerhans
Pubs id:: pubs:254599
UUID:: uuid:8f68faec-359d-457c-9405-2eb7d157437a
Local pid:: pubs:254599
Source identifiers:: 254599
Deposit date:: 2012-12-19

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Licence:: Terms and Conditions of Use for Oxford University Research Archive

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Journal article

The ratio between class II and class I collagenase determines the amount of neutral protease activity required for efficient islet release from the rat pancreas.

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