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Peri-operative interventions, but not inflammatory mediators, increase risk of acute kidney injury after cardiac surgery: a prospective cohort study.

Abstract:

PURPOSE: Cardiopulmonary bypass (CPB)-related inflammatory response might be one mechanism by which cardiac surgery associated acute kidney injury (CS-AKI) occurs. Interventions that may attenuate inflammation, including glucocorticoids or phosphodiesterase inhibitors, could therefore have a role in its prevention. We aimed to determine the role of inflammatory mediators in CS-AKI in children and the efficacy of commonly used peri-operative interventions to reduce CS-AKI risk. METHODS: We pr...

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Publication status:
Published

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Publisher copy:
10.1007/s00134-013-2849-4

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Journal:
Intensive care medicine More from this journal
Volume:
39
Issue:
5
Pages:
934-941
Publication date:
2013-05-01
DOI:
EISSN:
1432-1238
ISSN:
0342-4642
Language:
English
Keywords:
Pubs id:
pubs:387189
UUID:
uuid:8f5f469b-a8ae-4510-9160-bed8dc024d2e
Local pid:
pubs:387189
Source identifiers:
387189
Deposit date:
2013-11-16

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