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Ischaemic preconditioning of skeletal muscle 2. Investigation of the potential mechanisms involved.

Abstract:

We have previously shown that prior exposure of rat hind limbs to ischaemia for five minutes and reperfusion for five minutes reduced the structural damage to skeletal muscle which followed a subsequent period of ischaemia for four hours and reperfusion for one hour. We have now examined the potential mechanisms by which this ischaemic preconditioning protocol may be effective in reducing damage to skeletal muscle induced by prolonged ischaemia and reperfusion. Prior exposure of the hindlimb ...

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Publisher copy:
10.1302/0301-620x.84b8.9362

Authors


Bushell, AJ More by this author
Klenerman, L More by this author
Grierson, I More by this author
McArdle, A More by this author
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Journal:
The Journal of bone and joint surgery. British volume
Volume:
84
Issue:
8
Pages:
1189-1193
Publication date:
2002-11-05
DOI:
ISSN:
0301-620X
URN:
uuid:8f563a9c-07b4-4f9e-b582-ea6fce32f456
Source identifiers:
252317
Local pid:
pubs:252317

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