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SimBac: simulation of whole bacterial genomes with homologous recombination

Abstract:

Bacteria can exchange genetic material, or acquire genes found in theenvironment. This process, generally known as bacterial recombination, can have a strong impact on the evolution and phenotype of bacteria, for example causing the spread of antibiotic resistance across clades and species, but can also disrupt phylogenetic and transmission inferences. With the increasing affordability of whole genome sequencing, the need has emerged for an efficient simulator of bacterial evolution to test a...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1099/mgen.0.000044

Authors


Didelot, X More by this author
De Maio, N More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Wellcome Trust More from this funder
Publisher:
Microbiology Society Publisher's website
Journal:
Microbial Genomics Journal website
Publication date:
2015-12-11
DOI:
EISSN:
2057-5858
ISSN:
2057-5858
URN:
uuid:8f5282ee-5346-415a-898f-161349125ec8
Source identifiers:
581680
Local pid:
pubs:581680
Language:
English

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