Journal article icon

Journal article

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells.

Abstract:

The whole-cell configuration of the patch-clamp technique was used to characterize the biophysical and pharmacological properties of an oscillating K(+)-current that can be induced by intracellular application of GTP[gamma S] in mouse pancreatic B cells (Ammälä et al. 1991). These K+ conductance changes are evoked by periodic increases in the cytoplasmic Ca2+ concentration ([Ca2+]i) and transiently repolarize the B cell, thus inhibiting action-potential firing and giving rise to a bursting pa...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/bf00375069

Authors


Ammälä, C More by this author
Bokvist, K More by this author
Larsson, O More by this author
Berggren, PO More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
Pflugers Archiv : European journal of physiology
Volume:
422
Issue:
5
Pages:
443-448
Publication date:
1993-02-05
DOI:
EISSN:
1432-2013
ISSN:
0031-6768
URN:
uuid:8f439942-4e3f-4f70-9e29-c5fc0d3cdb1a
Source identifiers:
8298
Local pid:
pubs:8298

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP