Journal article icon

Journal article

Hebbian LTP in feed-forward inhibitory interneurons and the temporal fidelity of input discrimination.

Abstract:

Cortical information processing requires a delicate balance of excitatory and inhibitory signaling. How is this balance preserved during hippocampal memory encoding, which involves NMDA receptor-dependent long term potentiation (LTP)? This form of LTP occurs at synapses between pyramidal neurons but has not been detected in feed-forward inhibitory interneurons. We show that paired pre- and postsynaptic activity evokes pathway-specific LTP in half of rat stratum radiatum interneurons if cytopl...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/nn1486
Journal:
Nature neuroscience More from this journal
Volume:
8
Issue:
7
Pages:
916-924
Publication date:
2005-07-01
DOI:
EISSN:
1546-1726
ISSN:
1097-6256
Language:
English
Keywords:
Pubs id:
pubs:222061
UUID:
uuid:8f0553a4-c728-4012-928d-142db9566e27
Local pid:
pubs:222061
Source identifiers:
222061
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP