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A human lymphocyte-associated antigen involved in cell-mediated lympholysis.

Abstract:

Human lymphocyte function antigen (HLFA) is a cell surface protein defined by two monoclonal antibodies MHM23 and MHM24. It is present on both B and T lymphocytes but in greater amounts on the latter. Both antibodies precipitated antigen, from radiolabeled HSB-2 cells, which ran as two chains on sodium dodecyl sulfate polyacrylamide gel electrophoresis at 180 and 94 kDa. Neither antibody inhibited binding of the other, indicating that distinct epitopes were recognized. Both antibodies were sh...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830130305

Authors


Hildreth, JE More by this author
Hildreth, PD More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Target Discovery Institute
Journal:
European journal of immunology
Volume:
13
Issue:
3
Pages:
202-208
Publication date:
1983-03-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:8efd7254-908d-4694-a066-86a26b050667
Source identifiers:
42124
Local pid:
pubs:42124

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