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Journal article

Protein structure determination by electron cryo-microscopy.

Abstract:

Transmission electron cryo-microscopy (cryoEM) is a versatile tool in the structural analysis of proteins and biological macromolecular assemblies. In this review, we present a brief survey of the methods used in cryoEM, and their current developments. These latest advances provide exciting opportunities for the three-dimensional structural determination of macromolecular complexes that are either too large or too heterogeneous to be investigated by conventional X-ray crystallography or nucle...

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Publication status:
Published

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Publisher copy:
10.1016/j.coph.2009.04.006

Authors


Journal:
Current opinion in pharmacology
Volume:
9
Issue:
5
Pages:
636-642
Publication date:
2009-10-05
DOI:
EISSN:
1471-4973
ISSN:
1471-4892
URN:
uuid:8ef83c1c-f2a7-4c27-b000-307e27dfe785
Source identifiers:
100345
Local pid:
pubs:100345

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