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The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers.

Abstract:

RATIONALE: Cognitive impairment is a common feature of depressive illness. While accumulating evidence suggests that brain serotonin (5-HT) pathways play an important role in the neurobiology of depression, the extent to which altered 5-HT function is responsible for the associated changes in cognition and emotion remains unclear. OBJECTIVE: The present study examined the effects of acute dietary depletion of tryptophan (TRP) on cognitive and affective processing in healthy volunteers and exp...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-002-1128-9

Authors


Murphy, FC More by this author
Robbins, TW More by this author
Sahakian, BJ More by this author
Journal:
Psychopharmacology
Volume:
163
Issue:
1
Pages:
42-53
Publication date:
2002-08-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:8eeefbe2-d485-4665-89e4-3aed9c120228
Source identifiers:
185866
Local pid:
pubs:185866

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