Journal article icon

Journal article

Asymmetric total syntheses and structure confirmation of chlorofucins and bromofucins

Abstract:

Substrate-controlled asymmetric total syntheses and structure confirmation of (+)-(3E)- and (-)-(3Z)-chlorofucin [(E)-1 a and (Z)-1 a], and (+)-(3E)- and (-)-(3Z)-bromofucin [(E)-1 b and (Z)-1 b] were accomplished. Our syntheses feature as key steps haloetherification (either 'conventional' or 'one-pot organoselenium-mediated') of α,α'-trans-γ,δ-unsaturated oxocene alcohol 9 and our (E)- and (Z)-selective cross-metathesis (CM) protocols. More importantly, a rationale is provided for the strik...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/chem.201704564

Authors


More by this author
Role:
Author
ORCID:
0000-0003-4079-8734
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Oxford college:
St Hilda's College
Role:
Author
ORCID:
0000-0002-0104-4166
Publisher:
Wiley Publisher's website
Journal:
Chemistry - A European Journal Journal website
Volume:
24
Issue:
11
Pages:
2634-2642
Publication date:
2018-01-25
Acceptance date:
2017-12-09
DOI:
EISSN:
1521-3765
ISSN:
0947-6539
Pmid:
29222867
Source identifiers:
811184
Language:
English
Keywords:
Pubs id:
pubs:811184
UUID:
uuid:8ec23ed7-f8d9-4481-98a0-868fd2a37f1d
Local pid:
pubs:811184
Deposit date:
2018-04-12

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP