- Abstract:
-
C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of self and non-self ligands via its heterotrimeric globular (gC1q) domain and thus trigger the classical pathway. The trimeric gC1q signature domain has been identified in a variety of non-complement proteins that can be grouped together as a C1q family. The X-ray c...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.imbio.2006.11.001
-
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- Journal:
- Immunobiology
- Volume:
- 212
- Issue:
- 4-5
- Pages:
- 253-266
- Publication date:
- 2007
- DOI:
- EISSN:
-
1878-3279
- ISSN:
-
0171-2985
- URN:
-
uuid:8ebeb3b2-4fff-43e1-8116-9c697416c2a6
- Source identifiers:
-
243065
- Local pid:
- pubs:243065
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
C1q and its growing family.
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