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Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

Abstract:

Background Multiple early reports of patients admitted to hospital with COVID-19 showed that patients with chronic respiratory disease were significantly under-represented in these cohorts. We hypothesised that the widespread use of inhaled glucocorticoids among these patients was responsible for this finding, and tested if inhaled glucocorticoids would be an effective treatment for early COVID-19.

Methods We performed an open-label, parallel-group...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S2213-2600(21)00160-0

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Lancet Respiratory Medicine Journal website
Volume:
9
Issue:
7
Pages:
763-772
Publication date:
2021-04-09
Acceptance date:
2021-03-19
DOI:
ISSN:
2213-2600
Language:
English
Keywords:
Pubs id:
1170382
Local pid:
pubs:1170382
Deposit date:
2021-04-03

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