Journal article icon

Journal article

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

Abstract:

To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid arthritis (cases) and 20,169 controls of European descent, followed by replication in an independent set of 6,768 rheumatoid arthritis cases and 8,806 controls. Of 34 SNPs selected for replication, 7 new rheumatoid arthritis risk alleles were identified at genome-wide significance (P < 5 x 10(-8)) in an analysis...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/ng.582

Authors


Expand authors...
Journal:
Nature genetics
Volume:
42
Issue:
6
Pages:
508-514
Publication date:
2010-06-01
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Source identifiers:
108818
Language:
English
Keywords:
Pubs id:
pubs:108818
UUID:
uuid:8e98eb7e-15df-46ed-b4ad-9667204cbcab
Local pid:
pubs:108818
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP