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The effect of a nutritional source of tryptophan on dieting-induced changes in brain 5-HT function.

Abstract:

BACKGROUND: Dieting in healthy women results in a decrease in the availability of tryptophan (TRP), the amino-acid precursor of serotonin (5-HT), for brain 5-HT synthesis. This is associated with increases in the prolactin response to 5-HT drug challenge suggesting a 'supersensitivity' of 5-HT neuroendocrine responses. The aim of the study was to assess whether increased TRP intake during dieting would prevent the changes in TRP availability and 5-HT neuroendocrine function. METHOD: Fifty fem...

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Publication status:
Published

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Publisher copy:
10.1017/s0033291703008547

Authors


Attenburrow, MJ More by this author
Williams, C More by this author
Odontiadis, J More by this author
Van de Ouderaa, F More by this author
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Journal:
Psychological medicine
Volume:
33
Issue:
8
Pages:
1381-1386
Publication date:
2003-11-05
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:8e9557c8-c9e4-478b-9088-7e110e97dde8
Source identifiers:
185795
Local pid:
pubs:185795

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