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Journal article

Bacterial production and solution NMR studies of a viral membrane ion channel.

Abstract:

Advances in solution nuclear magnetic resonance (NMR) methodology that enable studies of very large proteins have also paved the way for studies of membrane proteins that behave like large proteins due to the added weight of surfactants. Solution NMR has been used to determine the high-resolution structures of several small, membrane proteins dissolved in detergent micelles and small bicelles. However, the usual difficulties with membrane proteins in producing, purifying, and stabilizing the ...

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Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
831
Pages:
165-179
Publication date:
2012-01-01
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Source identifiers:
222307
Language:
English
Keywords:
Pubs id:
pubs:222307
UUID:
uuid:8e8544f8-08dc-42d6-8301-caa5bab8374d
Local pid:
pubs:222307
Deposit date:
2012-12-19

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