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Journal article

Functions of nonclassical MHC and non-MHC-encoded class I molecules.

Abstract:

Fascinating recent discoveries have focused attention on the nonclassical class I molecules. They can exert their function at most levels of the immune response, being part of both innate and adaptive immune systems. They not only have specialized antigen-presentation functions but also play important immunoregulatory roles: HLA-E regulates natural killer cells by interacting with CD94/NKG2 receptors; the MIC (MHC class I chain related) glycoproteins appear crucial to the activation of gammad...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Current opinion in immunology More from this journal
Volume:
11
Issue:
1
Pages:
100-108
Publication date:
1999-02-01
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
Language:
English
Keywords:
Pubs id:
pubs:31433
UUID:
uuid:8e6e41ac-4619-45e9-a36f-aa70fe451bc7
Local pid:
pubs:31433
Source identifiers:
31433
Deposit date:
2012-12-19

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