The aim of this D.Phil was to develop a range of cyclisation cascades, which initially form a reactive iminium intermediates that can then be attacked by a pendant nucleophile resulting in novel polycyclic structures.
This concept has been applied to the development of three methodologies and has resulted in the discovery of new reactivity as well as the synthesis of a wide range of interesting novel structures
Chapter 1: Enantioselective chiral-BINOL-phosphoric acid cata...Expand abstract
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- Alex Gregory
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