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Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humans.

Abstract:

In healthy humans, changes in cardiac output are commonly accommodated with minimal change in pulmonary artery pressure. Conversely, exposure to hypoxia is associated with substantial increases in pulmonary artery pressure. In this study we used non-invasive measurement of an index of pulmonary artery pressure, the maximum systolic pressure difference across the tricuspid valve (DeltaPmax), to examine the pulmonary vascular response to changes in blood flow during both air breathing and hypox...

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Publication status:
Published

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Publisher copy:
10.1007/s00424-005-1422-6

Authors


Balanos, GM More by this author
Talbot, NP More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Pflugers Archiv : European journal of physiology
Volume:
450
Issue:
6
Pages:
372-380
Publication date:
2005-09-05
DOI:
EISSN:
1432-2013
ISSN:
0031-6768
URN:
uuid:8e5ef62b-dfe9-454f-9199-c5ed37e0963a
Source identifiers:
113809
Local pid:
pubs:113809

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