Journal article icon

Journal article

Extended follow-up following a phase 2b randomized trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya.

Abstract:

BACKGROUND: "FFM ME-TRAP" is sequential immunisation with two attenuated poxvirus vectors (FP9 and modified vaccinia virus Ankara) delivering the pre-erythrocytic malaria antigen ME-TRAP. Over nine months follow-up in our original study, there was no evidence that FFM ME-TRAP provided protection against malaria. The incidence of malaria was slightly higher in children who received FFM ME-TRAP, but this was not statistically significant (hazard ratio 1.5, 95% CI 1.0-2.3). Although the study w...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0000707

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Expand authors...
More from this funder
Funding agency for:
Bejon, P
Grant:
training fellowship (073597
More from this funder
Funding agency for:
Hill, A
Wellcome Trust More from this funder
Gates Malaria Partnership, London School of Hygiene and Tropical Medicine More from this funder
More from this funder
Funding agency for:
Marsh, K
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
2
Issue:
8
Article number:
e707
Publication date:
2007-01-01
DOI:
EISSN:
1932-6203
ISSN:
1555-5887
Source identifiers:
40644
Language:
English
Keywords:
UUID:
uuid:8e4c6b26-675b-4970-9983-7afa99a335ee
Local pid:
pubs:40644
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP