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Associations of human Leukocyte Antigen-DRB1 Alleles with Nasopharyngeal Carcinoma and its clinical significance in Xinjiang Uyghur autonomous region of China

Abstract:

Genetic susceptibility is one of the major etiological factors for nasopharyngeal carcinoma (NPC). Among the genetic predisposing factors, human leukocyte antigen (HLA) genes have been reported to be associated with NPC. This study aimed to investigate the associations of HLA-DRB1 alleles with NPC and the clinical significance of HLA-DRB1 alleles in NPC.From January 2009 to December 2013, 140 NPC patients (118 Han patients and 22 Uyghur patients) and 158 healthy controls (81 Han individuals a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4103/0366-6999.182833

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More from this funder
Name:
Key Laboratory Projects of Xinjiang Uygur Autonomous Region
Grant:
2015KL021
More from this funder
Name:
Autonomous Region Achievement Promotion Projects
Grant:
201554142
More from this funder
Name:
International Cooperation Projects of Ministry of Science and Technology
Grant:
2012DFA31560
Publisher:
Medknow Publications
Journal:
Chinese Medical Journal More from this journal
Volume:
129
Issue:
11
Pages:
1347-1354
Publication date:
2016-06-05
Acceptance date:
2016-04-20
DOI:
ISSN:
0366-6999
Pmid:
27231174
Language:
English
Keywords:
Pubs id:
pubs:625227
UUID:
uuid:8e47618a-76b7-41f0-8055-347f77a78ef5
Local pid:
pubs:625227
Source identifiers:
625227
Deposit date:
2016-11-09

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