- Abstract:
-
Induction of mild states of hyperketonemia may improve physical and cognitive performance. In this study, we determined the kinetic parameters, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate, a ketone monoester administered in the form of a meal replacement drink to healthy human volunteers. Plasma levels of β-hydroxybutyrate and acetoacetate were elevated following administration of a single dose of the ketone monoester, whether at 140, 357, or 714 mg/kg body weight, whi...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.yrtph.2012.04.008
-
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- Journal:
- Regulatory toxicology and pharmacology : RTP
- Volume:
- 63
- Issue:
- 3
- Pages:
- 401-408
- Publication date:
- 2012-08-05
- DOI:
- EISSN:
-
1096-0295
- ISSN:
-
0273-2300
- URN:
-
uuid:8e3b5c91-12e6-453a-ac7f-a266e19e4926
- Source identifiers:
-
329036
- Local pid:
- pubs:329036
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects.
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