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Journal article

Role of Macrophages in Autoimmunity

Abstract:

Macrophages contribute to autoimmune diseases and inflammation through their ability to present autoantigens and through their potent effector mechanisms unleashed during innate and acquired cellular and humoral immunity. We describe macrophage receptors that recognize and respond to modified self and foreign ligands, mediating homeostatic clearance of dying cells and their products, as well as altered gene expression, secretion of cytocidal products and host defense against infection. A rang...

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Journal:
Autoimmune Diseases: Fifth Edition More from this journal
Pages:
161-174
Publication date:
2013-12-01
DOI:
Pubs id:
pubs:472225
UUID:
uuid:8e3520d5-4da3-4155-83e5-2b322901829c
Local pid:
pubs:472225
Source identifiers:
472225
Deposit date:
2014-07-11

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