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The effect of basal vasodilation on hypercapnic and hypocapnic reactivity measured using magnetic resonance imaging.

Abstract:

Cerebrovascular reactivity to vasodilatory hypercapnic and vasoconstrictive hypocapnic challenges is known to be altered in several hemodynamic disorders, which is often attributable to changes in smooth muscle-mediated vascular compliance. Recently, attenuated reactivity to hypercapnia but enhanced reactivity to hypocapnia was observed in patients with chronic stroke. We hypothesize that the latter observation could be explained by a change in the basal vascular tone. In particular, reduced ...

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Publication status:
Published

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Publisher copy:
10.1038/jcbfm.2010.187

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism More from this journal
Volume:
31
Issue:
2
Pages:
426-438
Publication date:
2011-02-01
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
Language:
English
Keywords:
Pubs id:
pubs:241967
UUID:
uuid:8e252e67-53c3-400f-be14-c195dcb197d6
Local pid:
pubs:241967
Source identifiers:
241967
Deposit date:
2012-12-19

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