Immunogenicity and induction of immunological memory of the heptavalent pneumococcal conjugate vaccine in preterm UK infants

Journal article

Data on the immunogenicity and memory induction of pneumococcal conjugate vaccines in very preterm infants is limited. We vaccinate 69 full term and 68 preterm infants (median gestational age (GA) 30 weeks) with a 7-valent pneumococcal conjugate vaccine (PCV7) at 2/3/4 months of age, followed by a plain polysaccharide booster at 12 months of age. IgG-GMC (ELISA) was significantly lower in preterm infants to six vaccine serotypes (ST) at 2 months and 5 months of age, to five ST at 12 months of...

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Authors: Ruggeberg, J; Collins, C; Clarke, P; Johnson, N; Sinha, R

• Journal: Vacunas
• Volume: 8
• Issue: 2
• Pages: 82-90
• Publication date: 2007-04-01
• EISSN: 1578-8857
• ISSN: 1576-9887
• Language: Spanish; Castilian
• Keywords: Pneumococcal conjugate vaccine; Prematurity; Immunological memory