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Different kenyon cell populations drive learned approach and avoidance in Drosophila

Abstract:

In Drosophila, anatomically discrete dopamine neurons that innervate distinct zones of the mushroom body (MB) assign opposing valence to odors during olfactory learning. Subsets of MB neurons have temporally unique roles in memory processing, but valence-related organization has not been demonstrated. We functionally subdivided the αβ neurons, revealing a value-specific role for the ~160 αβ core (αβc) neurons. Blocking neurotransmission from αβ surface (αβs) neur...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
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Publisher copy:
10.1016/j.neuron.2013.07.045

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Publisher:
Elsevier (Cell Press) Publisher's website
Journal:
Neuron Journal website
Volume:
79
Issue:
5
Pages:
945-956
Publication date:
2013-09-04
Acceptance date:
2013-07-03
DOI:
EISSN:
1097-4199
ISSN:
0896-6273
URN:
uuid:8e1a530f-d8c5-470d-857d-27bb845bb512
Source identifiers:
426718
Local pid:
pubs:426718
Language:
English
Keywords:

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