Sleep and circadian rhythm disruption in neuropsychiatric illness.

Journal article

Sleep and circadian rhythm disruption (SCRD) is a common feature in many neuropsychiatric diseases including schizophrenia, bipolar disorder and depression. Although the precise mechanisms remain unclear, recent evidence suggests that this comorbidity is not simply a product of medication or an absence of social routine, but instead reflects commonly affected underlying pathways and mechanisms. For example, several genes intimately involved in the generation and regulation of circadian rhythm...

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Authors: Jagannath, A; Peirson, SN; Foster, R

• Publication status: Published
• Journal: Current opinion in neurobiology
• Volume: 23
• Issue: 5
• Pages: 888-894
• Publication date: 2013-10-01
• DOI: 10.1016/j.conb.2013.03.008
• EISSN: 1873-6882
• ISSN: 0959-4388
• Language: English
• Keywords: Humans; Mental Disorders; Sleep; Circadian Rhythm; Brain; Animals