Conference item
Generation of CD1 tetramers as a tool to monitor glycolipid-specific T cells.
- Abstract:
-
CD1 molecules are beta(2)m-associated HLA class-I-like glycoproteins which have the unique ability to present glycolipid and phospholipid antigens to specific T lymphocytes. To study the biology of CD1 and its role in human disease we developed novel techniques for generation of recombinant CD1/lipid complexes by in vitro refolding. Fluorescent tetrameric complexes made from soluble recombinant CD1d/alpha-galactosylceramide complexes allowed highly sensitive and specific ex vivo and in vitro ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Philosophical transactions of the Royal Society of London. Series B, Biological sciences
- Volume:
- 358
- Issue:
- 1433
- Pages:
- 875-877
- Publication date:
- 2003-05-01
- Event title:
- Discussion Meeting of the Royal-Society
- DOI:
- EISSN:
-
1471-2970
- ISSN:
-
0962-8436
- Source identifiers:
-
12063
Item Description
- Keywords:
- Pubs id:
-
pubs:12063
- UUID:
-
uuid:8e0d58c7-fb88-4a4b-95bf-8b38a9e14ed1
- Local pid:
- pubs:12063
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2003
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