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Thesis

HLA-B51 associated HIV-1 viral control

Abstract:

Polymorphism in the Human Leucocyte Antigen (HLA) region of chromosome is the major source of host genetic variability in outcome of HIV-1 infection. However, there is limited understanding of the mechanisms underlying the beneficial effect of protective class I alleles such as HLA-B57, B27 and B51.

Taking advantage of a unique cohort (SM cohort) infected with clade B’ HIV-1 through contaminated blood, in which many variables, such as the length of infection, the infecting viral str...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Sarah Rowland-Jones and Tao Dong's Group Institute of molecular Medicine
Oxford college:
Wolfson College
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:8e06bed0-bd8d-4774-b137-c12f5e3547fc
Local pid:
ora:10140
Deposit date:
2015-02-20

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