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Journal article

Functional motifs in biochemical reaction networks.

Abstract:

The signal-response characteristics of a living cell are determined by complex networks of interacting genes, proteins, and metabolites. Understanding how cells respond to specific challenges, how these responses are contravened in diseased cells, and how to intervene pharmacologically in the decision-making processes of cells requires an accurate theory of the information-processing capabilities of macromolecular regulatory networks. Adopting an engineer's approach to control systems, we ask...

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Publication status:
Published

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Journal:
Annual review of physical chemistry
Volume:
61
Issue:
1
Pages:
219-240
Publication date:
2010
DOI:
EISSN:
1545-1593
ISSN:
0066-426X
URN:
uuid:8e02f4e6-4f9a-4fbd-854e-566027f4bce0
Source identifiers:
100438
Local pid:
pubs:100438

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