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Acidosis of severe falciparum malaria: heading for a shock?

Abstract:

Severe Plasmodium falciparum malaria encompasses a complex syndrome affecting many organs and causing physiological perturbations that have many features in common with children with sepsis. Among these, metabolic acidosis has emerged as a central feature of severe malaria and is the best independent predictor of a fatal outcome in both adults and children. There is now clear evidence that intravascular hypovolaemia (shock) is common in children with malarial acidosis. How it should be treate...

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Publication status:
Published

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Publisher copy:
10.1016/j.pt.2004.10.010

Authors


Journal:
Trends in parasitology
Volume:
21
Issue:
1
Pages:
11-16
Publication date:
2005-01-01
DOI:
EISSN:
1471-5007
ISSN:
1471-4922
Source identifiers:
185623
Language:
English
Keywords:
Pubs id:
pubs:185623
UUID:
uuid:8e0026ed-659c-4c12-92c1-dfdee220db71
Local pid:
pubs:185623
Deposit date:
2012-12-19

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