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Acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells.

Abstract:

1. This study investigates the acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells. 2. After incubation of intact cells with 0.1 mmol/l 5-aminosalicylic acid, N-acetyl-5-aminosalicylic acid was detected in a concentration of 141 (+/- 23.8 SEM) nmol/g dry weight in the incubation medium, and 34.8 (+/- 5.5 SEM) nmol/g dry weight intracellularly. No unchanged 5-aminosalicylic acid was detected inside the cell. 3. Acetylation of 5-aminosalicylic acid by a cell homogena...

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Publication status:
Published

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Journal:
Clinical science (London, England : 1979) More from this journal
Volume:
78
Issue:
1
Pages:
105-111
Publication date:
1990-01-01
EISSN:
1470-8736
ISSN:
0143-5221
Language:
English
Keywords:
Pubs id:
pubs:135389
UUID:
uuid:8dff0385-be82-4470-88b4-08c0ace69d82
Local pid:
pubs:135389
Source identifiers:
135389
Deposit date:
2012-12-19

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