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Chloroquine-resistant Plasmodium malariae in south Sumatra, Indonesia.

Abstract:

Oral chloroquine is the treatment of choice for uncomplicated Plasmodium malariae infections worldwide. We did a prospective 28-day in-vivo assessment of the efficacy of chloroquine for treatment of P malariae on Legundi Island in Lampung Bay, Sumatra, Indonesia. Of 28 patients, one had recurrent parasitaemia on day 28, and two had persistent parasitaemia to day 8. Whole-blood chloroquine and desethylchloroquine concentrations were at ordinarily effective levels (> or = 100 microg/L) on da...

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Publication status:
Published

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Authors


Maguire, JD More by this author
Sumawinata, IW More by this author
Laksana, B More by this author
Prodjodipuro, P More by this author
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Journal:
Lancet
Volume:
360
Issue:
9326
Pages:
58-60
Publication date:
2002-07-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:8dec3ebf-e99e-4f2c-bbb3-fa76fa2d7b9d
Source identifiers:
81710
Local pid:
pubs:81710

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