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Bridging the gap between genetic associations and molecular mechanisms for type 2 diabetes.

Abstract:

Type 2 diabetes is a global pandemic for which there is currently no disease-modifying treatment. New and targeted therapeutics are greatly needed, but progress in identifying novel targets for therapeutic intervention is severely hampered by poor understanding of disease pathogenesis. Over the past 6 years, the success of genome-wide association studies has led to an unprecedented increase in the number of loci robustly associating with type 2 diabetes risk. Each of these signals offers the ...

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Publisher copy:
10.1007/s11892-013-0429-1

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Current diabetes reports More from this journal
Volume:
13
Issue:
6
Pages:
778-785
Publication date:
2013-12-01
DOI:
EISSN:
1539-0829
ISSN:
1534-4827
Language:
English
Keywords:
Pubs id:
pubs:434337
UUID:
uuid:8de43b75-f0be-4902-bfe4-808f5b131b81
Local pid:
pubs:434337
Source identifiers:
434337
Deposit date:
2014-08-11

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