- Abstract:
-
Annexin 1 (ANX-A1) exerts antimigratory actions in several models of acute and chronic inflammation. This is related to its ability to mimic the effect of endogenous ANX-A1 that is externalized on neutrophil adhesion to the postcapillary endothelium. In the present study we monitored ANX-A1 expression and localization in intravascular and emigrated neutrophils, using a classical model of rat peritonitis. For this purpose, a pair of antibodies raised against the ANX-A1 N-terminus (ie, able to ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0002-9440(10)64002-3
-
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- Journal:
- The American journal of pathology
- Volume:
- 158
- Issue:
- 2
- Pages:
- 603-615
- Publication date:
- 2001-02-05
- DOI:
- EISSN:
-
1525-2191
- ISSN:
-
0002-9440
- URN:
-
uuid:8db37ec5-4fd6-4819-8bd5-d6cc4b201144
- Source identifiers:
-
114502
- Local pid:
- pubs:114502
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression.
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