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The impact of protein characterization in structural proteomics.

Abstract:

Protein characterization plays a role in two key aspects of structural proteomics. The first is the quality assessment of the produced protein preparations. Obtaining well diffracting crystals is one of the major bottlenecks in the structure-determination pipeline. Often, this is caused by the poor quality of the protein preparation used for crystallization trials. Hence, it is essential to perform an extensive quality assessment of the protein preparations prior to crystallization and to use...

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Publication status:
Published

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Publisher copy:
10.1107/s0907444906030307

Authors


Geerlof, A More by this author
Coutard, B More by this author
Egloff, MP More by this author
Enguita, FJ More by this author
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Journal:
Acta crystallographica. Section D, Biological crystallography
Volume:
62
Issue:
Pt 10
Pages:
1125-1136
Publication date:
2006-10-05
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
URN:
uuid:8da317c2-b6a6-4ad7-8274-e8cee6fc4300
Source identifiers:
40075
Local pid:
pubs:40075

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