Journal article
Synovial fluid fingerprinting in end-stage knee osteoarthritis: a novel biomarker concept
- Abstract:
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Aims: The lack of disease-modifying treatments for osteoarthritis (OA) is linked to a shortage of suitable biomarkers. This study combines multi-molecule synovial fluid analysis with machine learning to produce an accurate diagnostic biomarker model for end-stage knee OA (esOA).
Methods: Synovial fluid (SF) from patients with esOA, non-OA knee injury, and inflammatory knee arthritis were analyzed for 35 potential markers using immunoassays. Partial...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, 1.0MB)
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- Publisher copy:
- 10.1302/2046-3758.99.bjr-2019-0192.r1
Authors
Bibliographic Details
- Publisher:
- British Editorial Society of Bone & Joint Surgery Publisher's website
- Journal:
- Bone and Joint Research Journal website
- Volume:
- 9
- Issue:
- 9
- Pages:
- 623-632
- Publication date:
- 2020-09-30
- DOI:
- EISSN:
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2046-3758
- ISSN:
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2046-3758
- Pmid:
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33101658
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1135954
- Local pid:
- pubs:1135954
- Deposit date:
- 2020-11-10
Terms of use
- Copyright holder:
- Jayadev et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 Author(s) et al. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/ by-nc-nd/4.0/.
- Licence:
- CC Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)
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