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Journal article

Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load.

Abstract:

The potent ability of current antiretroviral drug regimens to control human immunodeficiency Virus-1 (HIV-1) replication, in conjunction with the clinical practice of structured therapeutic interruptions, provides a system in which virus levels are manipulated during a persistent infection in humans. Here, we exploit this system to examine the impact of variable plasma virus load (pVL) on the functionality of HIV-specific CD8+ T-lymphocyte populations. Using both ELISpot methodology and intra...

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Publication status:
Published

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Publisher copy:
10.1023/a:1020656300027

Authors


Journal:
Journal of clinical immunology More from this journal
Volume:
22
Issue:
6
Pages:
363-374
Publication date:
2002-11-01
DOI:
EISSN:
1573-2592
ISSN:
0271-9142
Language:
English
Keywords:
Pubs id:
pubs:17292
UUID:
uuid:8d997be4-074a-4600-89b1-e278e5bc8d9a
Local pid:
pubs:17292
Source identifiers:
17292
Deposit date:
2012-12-19

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