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Angiogenesis and the tumour hypoxia response in prostate cancer: a review.

Abstract:

The formation of new blood vessels, angiogenesis, is a highly-regulated active process that is critical for the development of the normal and malignant prostate. The vascular endothelial growth factor (VEGF) system assumes a critical role in the angiogenic process. Angiogenesis is a prerequisite for the expansion of solid tumours beyond 1-3 mm3 and is stimulated in response to a hypoxic environment. This review discusses the process of angiogenesis and the key angiogenic mediator, VEGF, and t...

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Publisher copy:
10.1016/j.ijsu.2005.03.013

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
International journal of surgery (London, England) More from this journal
Volume:
3
Issue:
1
Pages:
61-67
Publication date:
2005-01-01
DOI:
EISSN:
1743-9159
ISSN:
1743-9191
Language:
English
Keywords:
Pubs id:
pubs:414595
UUID:
uuid:8d9444f6-4d92-4592-bb78-73f1aa5c2ac5
Local pid:
pubs:414595
Source identifiers:
414595
Deposit date:
2013-11-16

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