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Journal article

Switching off micturition using deep brain stimulation at midbrain sites.

Abstract:

Most of the time the bladder is locked in storage mode, switching to voiding only when it is judged safe and/or socially appropriate to urinate. Here we show, in humans and rodents, that deep brain stimulation in the periaqueductal gray matter can rapidly and reversibly manipulate switching within the micturition control circuitry, to defer voiding and maintain urinary continence, even when the bladder is full. Manipulation of neural continence pathways by deep brain stimulation may offer new...

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Publication status:
Published

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Publisher copy:
10.1002/ana.23571

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Annals of neurology More from this journal
Volume:
72
Issue:
1
Pages:
144-147
Publication date:
2012-07-01
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
Language:
English
Keywords:
Pubs id:
pubs:310171
UUID:
uuid:8d89725a-304b-4606-ae45-85dbfca94187
Local pid:
pubs:310171
Source identifiers:
310171
Deposit date:
2012-12-19

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