Journal article
Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology.
- Abstract:
-
Individual eukaryotic microbes, such as the kinetoplastid parasite Trypanosoma brucei, have a defined size, shape, and form yet transition through life cycle stages, each having a distinct morphology. In questioning the structural processes involved in these transitions, we have identified a large calpain-like protein that contains numerous GM6 repeats (ClpGM6) involved in determining T. brucei cell shape, size, and form. ClpGM6 is a cytoskeletal protein located within the flagellum along the...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- Rockefeller University Press Publisher's website
- Journal:
- Journal of Cell Biology Journal website
- Volume:
- 206
- Issue:
- 3
- Pages:
- 377-384
- Publication date:
- 2014-08-01
- Acceptance date:
- 2014-06-24
- DOI:
- EISSN:
-
1540-8140
- ISSN:
-
0021-9525
- Source identifiers:
-
479285
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:479285
- UUID:
-
uuid:8d819346-024d-43bd-9700-1d0dc945f598
- Local pid:
- pubs:479285
- Deposit date:
- 2014-08-17
Terms of use
- Copyright holder:
- Hayes et al
- Copyright date:
- 2014
- Notes:
- This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
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